Lewis肺癌手术与化疗联合治疗的效果
Effect of combined surgical and chemotherapeutic treatment of Lewis lung carcinoma.
作者信息
Szabó Z, Dworák O, Kopper L, Lapis K
出版信息
J Cancer Res Clin Oncol. 1980;97(2):161-6. doi: 10.1007/BF00409902.
Abstract
The effect of combined surgical and chemotherapeutic treatment on Lewis lung carcinoma was studied. The i.m. implanted primary tumor was removed on the 10th day after transplantation, and the survival of mice was registered. Cyclophosphamide proved to be the most effective among the drugs studied (Cyclophosphamide, 5-FU, DBD, CCNU, Adriamycin, Vincristin, Hexyldeoxyuridine). Using different schedules (pre- and/or post-operative treatment) the pre- and post-operative drug administration was the most advantageous. Combined therapy showed always better effect than monotherapy.
摘要
研究了手术与化疗联合治疗对Lewis肺癌的效果。移植后第10天切除经肌肉注射植入的原发性肿瘤，并记录小鼠的存活情况。在研究的药物（环磷酰胺、5-氟尿嘧啶、双溴丙脲、环己亚硝脲、阿霉素、长春新碱、己基脱氧尿苷）中，环磷酰胺被证明是最有效的。采用不同的给药方案（术前和/或术后治疗），术前和术后给药最为有利。联合治疗的效果始终优于单一疗法。
相似文献
1
Effect of combined surgical and chemotherapeutic treatment of Lewis lung carcinoma.Lewis肺癌手术与化疗联合治疗的效果
J Cancer Res Clin Oncol. 1980;97(2):161-6. doi: 10.1007/BF00409902.
2
Systemic treatments for metastatic cutaneous melanoma.转移性皮肤黑色素瘤的全身治疗
Cochrane Database Syst Rev. 2018 Feb 6;2(2):CD011123. doi: 10.1002/14651858.CD011123.pub2.
3
A rapid and systematic review of the clinical effectiveness and cost-effectiveness of paclitaxel, docetaxel, gemcitabine and vinorelbine in non-small-cell lung cancer.对紫杉醇、多西他赛、吉西他滨和长春瑞滨在非小细胞肺癌中的临床疗效和成本效益进行的快速系统评价。
Health Technol Assess. 2001;5(32):1-195. doi: 10.3310/hta5320.
4
Success and failure in the treatment of solid tumors. 3. "Cure" of metastatic Lewis lung carcinoma with methyl-CCNU (NSC-95442) and surgery-chemotherapy.
Cancer Chemother Rep. 1972 Apr;56(2):183-95.
5
Induction of apoptosis in metastatic foci from human gastric cancer xenografts in nude mice and reduction of circulating tumor cells in blood by 5-FU and 1-hexylcarbamoyl-5-fluorouracil.5-氟尿嘧啶和1-己基氨基甲酰基-5-氟尿嘧啶诱导裸鼠人胃癌异种移植瘤转移灶中的细胞凋亡并减少血液中的循环肿瘤细胞。
J Cancer Res Clin Oncol. 1999 Dec;125(12):660-8. doi: 10.1007/s004320050331.
6
The clinical effectiveness and cost-effectiveness of topotecan for small cell lung cancer: a systematic review and economic evaluation.拓扑替康治疗小细胞肺癌的临床疗效和成本效果：系统评价和经济评估。
Health Technol Assess. 2010 Mar;14(19):1-204. doi: 10.3310/hta14190.
7
The Black Book of Psychotropic Dosing and Monitoring.《精神药物剂量与监测黑皮书》
Psychopharmacol Bull. 2024 Jul 8;54(3):8-59.
8
Topotecan, pegylated liposomal doxorubicin hydrochloride and paclitaxel for second-line or subsequent treatment of advanced ovarian cancer: a systematic review and economic evaluation.拓扑替康、聚乙二醇化脂质体盐酸多柔比星和紫杉醇用于晚期卵巢癌二线或后续治疗：一项系统评价和经济学评估
Health Technol Assess. 2006 Mar;10(9):1-132. iii-iv. doi: 10.3310/hta10090.
9
Analysis of metastatic spread and growth of tumor cells in mice with depressed natural killer activity by anti-asialo GM1 antibody or anticancer agents.通过抗去唾液酸GM1抗体或抗癌药物对自然杀伤活性降低的小鼠体内肿瘤细胞的转移扩散和生长进行分析。
J Cancer Res Clin Oncol. 1984;107(3):157-63. doi: 10.1007/BF01032600.
10
Pre-operative endometrial thinning agents before endometrial destruction for heavy menstrual bleeding.对于月经过多患者，在进行子宫内膜破坏术前使用的术前子宫内膜减薄剂。
Cochrane Database Syst Rev. 2013 Nov 15;2013(11):CD010241. doi: 10.1002/14651858.CD010241.pub2.
引用本文的文献
1
Chemotherapeutic sensitivity of liver metastases from intrasplenically-growing Lewis lung tumor.
Clin Exp Metastasis. 1983 Oct-Dec;1(4):341-7. doi: 10.1007/BF00121196.
本文引用的文献
1
[Combination of surgery and chemotherapy in cancer; model experiment on a resistant tumor in the rat].
Munch Med Wochenschr. 1958 Dec 5;100(49):1913-8.
2
Effect of various chemotherapeutic agents on metastasis.多种化疗药物对转移的影响。
Br J Cancer. 1956 Dec;10(4):719-23. doi: 10.1038/bjc.1956.87.
3
Inhibition of tumor growth in syngeneic chimeric mice mediated by a depletion of suppressor T cells.通过消耗抑制性T细胞介导的同基因嵌合小鼠肿瘤生长抑制。
Transplantation. 1975 Jul;20(1):68-74. doi: 10.1097/00007890-197507000-00011.
4
Effects of surgery on the cell kinetics of residual tumor.手术对残留肿瘤细胞动力学的影响。
Cancer Treat Rep. 1976 Dec;60(12):1749-60.
5
Pulmonary metastases of the lewis lung tumor-cell kinetics and response to cyclophosphamide at different sizes.
Cancer Treat Rep. 1977 Jan-Feb;61(1):29-36.
6
Correlation of immune response with clinical stage in Lewis lung tumor-bearing mice.Lewis肺癌荷瘤小鼠免疫反应与临床分期的相关性
Oncology. 1978;35(4):155-9. doi: 10.1159/000225275.
7
Effectiveness of clinically active antineoplastic drugs in a surgical-adjuvant chemotherapy treatment regimen using the Lewis Lung (LL) carcinoma.使用Lewis肺癌（LL）的手术辅助化疗治疗方案中临床活性抗肿瘤药物的有效性。
Int J Cancer. 1978 Apr 15;21(4):482-9. doi: 10.1002/ijc.2910210414.
Zotero 插件