Jaffe N
Recent Results Cancer Res. 1978;65:68-72. doi: 10.1007/978-3-642-81249-1_10.
A review of published reports of the management of childhood non-Hodgkin's lymphoma was undertaken to determine the extent to which a staging procedure should be implemented and the benefits which could be derived. A variety of clinical, radiographic, surgical, and laboratory investigations were performed by different investigators. Overall, similar results were obtained for the different stages. The utility of the individual studies was not defined in any single review. However, it appeared that bone marrow biopsy was superior to bone marrow aspirates, staging laparotomy was generally not required, and lymphangiography did not constitute a routine staging procedure. Staging permitted identification of patients with primary sites at high risk for the development of central nervous system disease or failure. The reviews did not specify the minimum number of procedures to be performed. It is concluded that each patient should receive individual consideration, and diagnostic evaluation should consist of a series of tests sequentially performed and interrupted whenever sufficient information has been assembled for institution of therapy.
对已发表的儿童非霍奇金淋巴瘤治疗报告进行了综述，以确定应实施分期程序的程度以及可获得的益处。不同的研究者进行了各种临床、影像学、手术和实验室检查。总体而言，不同分期获得了相似的结果。在任何单一综述中都未明确各项研究的效用。然而，似乎骨髓活检优于骨髓穿刺，一般不需要进行分期剖腹术，淋巴管造影术也不构成常规分期程序。分期有助于识别原发性部位有发生中枢神经系统疾病或衰竭高风险的患者。综述未明确规定要进行的最少检查项目数量。结论是，应对每位患者进行个体化考量，诊断评估应包括一系列依次进行的检查，并在收集到足够信息以开始治疗时中断检查。
