Aoki Y, Recinos M M, Hashiguchi Y
J Parasitol. 1980 Oct;66(5):797-801.
Microfilariae of Onchocerca volvulus obtained from onchocercomas were inoculated subcutaneously into the inguinal region of mice. Microfilariae disseminated rapidly, invading the tail and lungs within 1 hr and the ears within 3 hr postinoculation. During the early period of infection microfilariae appeared in the eyes, ears, viscera, pelt, carcass, and tail; later, the microfilariae tended to accumulate in the tail. Liver microfilariae were recovered up to 12 wk postinoculation. Intraperitoneal inoculation and subcutaneous inoculation into the inguinal region resulted in the concentration of microfilariae in the tail, whereas inoculation into the scalp caused microfilarial accumulation in the ears.
从盘尾丝虫瘤获取的旋盘尾丝虫微丝蚴被皮下接种到小鼠的腹股沟区域。微丝蚴迅速扩散，接种后1小时内侵入尾部和肺部，3小时内侵入耳部。在感染早期，微丝蚴出现在眼睛、耳朵、内脏、皮毛、尸体和尾部；之后，微丝蚴倾向于在尾部聚集。接种后长达12周可在肝脏中发现微丝蚴。腹腔接种和腹股沟区域皮下接种导致微丝蚴在尾部聚集，而头皮接种则导致微丝蚴在耳部聚集。
