Shalev A, Hannan C K
J Clin Lab Immunol. 1980 Jul;4(1):59-62.
The hypothesis that Hepatitis B surface Antigen (HBsAg) is cross-reactive with the male-specific H-Y antigen has been tested. In none of three separate experiments using selected anti-HBs sera, or in a fourth experiment using anti-H-Y sera, could any evidence for cross-reactivity be detected. Our results are therefore not compatible with the idea that altered sex-ratios observed among offspring of parents infected with Hepatitis B virus are related to cross-reactivity between HBsAg and a male-associated antigen.
乙肝表面抗原（HBsAg）与雄性特异性H-Y抗原存在交叉反应的假说已得到验证。在三项分别使用选定的抗-HBs血清的独立实验中，以及在第四项使用抗-H-Y血清的实验中，均未检测到任何交叉反应的证据。因此，我们的结果与以下观点不相符：在感染乙肝病毒的父母的后代中观察到的性别比例变化与HBsAg和一种雄性相关抗原之间的交叉反应有关。
