Jogerst G J, Dippe S E
JAMA. 1981 Feb 27;245(8):842-6.
Antibiotic use in a community hospital was evaluated to demonstrate specialty variations. A chart review was performed using the Veterans Administration's "Guidelines for Peer Review" to determine appropriate antibiotic use. Of the 1,054 patients discharged in August 1977, three hundred ten (29.4%) received 479 courses of antibiotics of which two hundred eighty-seven (60%) were considered appropriate. Seventy-two percent of the therapeutic courses and 36% of the prophylactic courses were appropriate. Prophylactic antibiotics were used in 12% of the hospitalized patients and accounted for 33% of the total antibiotics. No notable difference in appropriate antibiotic use was found among general surgeons (73%), internists (72%), orthopedists (71%), and family practitioners (67%). Substantially lower levels were found among urologists (54%), otolaryngologists (44%), and obstetricians (36%). Continued education in proper antibiotic use is needed especially for prophylaxis. Educational programs directed at specific specialties may be the most fruitful way to effect improved overall antibiotic use.
对一家社区医院的抗生素使用情况进行了评估,以展示不同专科之间的差异。利用退伍军人管理局的“同行评审指南”进行病历审查,以确定抗生素的合理使用情况。在1977年8月出院的1054名患者中,310名(29.4%)接受了479个疗程的抗生素治疗,其中287个疗程(60%)被认为是合理的。治疗性疗程的72%和预防性疗程的36%是合理的。12%的住院患者使用了预防性抗生素,占抗生素使用总量的33%。普通外科医生(73%)、内科医生(72%)、骨科医生(71%)和家庭医生(67%)在合理使用抗生素方面没有显著差异。泌尿科医生(54%)、耳鼻喉科医生(44%)和产科医生(36%)的合理使用率明显较低。尤其在预防性使用抗生素方面,需要持续开展合理使用抗生素的教育。针对特定专科的教育项目可能是提高整体抗生素合理使用效果的最有效途径。