Naik S S, Gurnani S
Lepr India. 1980 Oct;52(4):501-7.
Serum lysozyme was assessed in 43 healthy subjects and 183 leprosy patients. Significantly elevated level of lysozyme was observed in sera of leprosy patients as compared to normal individuals. The enzyme levels in leprosy of different types showed elevations in following order, Erythema Nodosum Leprosum (ENL) greater than Lepromatous greater than Borderline greater than Tuberculoid. Enzyme levels in patients with inactive stage were lower than in untreated patients. The serum lysozyme level correlated well with the activity disease in leprosy--clinically and bacteriologically. Thus the estimation of serum lysozyme can be used as one of the parameters of activity of the disease.
对43名健康受试者和183名麻风病患者的血清溶菌酶进行了评估。与正常个体相比，麻风病患者血清中的溶菌酶水平显著升高。不同类型麻风病患者的酶水平升高顺序如下：结节性红斑型麻风（ENL）大于瘤型大于界线类大于结核样型。静止期患者的酶水平低于未治疗患者。血清溶菌酶水平与麻风病的疾病活动在临床和细菌学方面密切相关。因此，血清溶菌酶的测定可作为该疾病活动的参数之一。
