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在加的斯分离的志贺氏菌菌株的抗生素耐药性(作者译)

[Antibiotic resistance of Shigella strains isolated in Cádiz (author's transl)].

作者信息

García Martos P, Marín Casanova P, García Herruzo J, Fernández Gutiérrez del Alamo C

出版信息

Med Clin (Barc). 1980 Dec 15;75(10):425-9.

PMID:7464328
Abstract

The incidence of shigellosis at the Residencia Sanitaria Fernando Zamacola (Cáciz, Spain) and the antibiotic sensitivity of 94 strains of Shigella sonnei and 40 strains of Shigella flexneri, isolated during the year 1979, has been studied taking into account the present status of strain resistance to the major antibiotics. Three epidemic bouts of shigellosis were detected: one in february by Shigella sonnei (16 cases), and two others in august-september and november due to Shigella flexneri (43 and 29 cases). Children 2 to 5 years old had the highest incidence of Shigella infection. Almost all strains isolated were resistant to the sulphonamides (99.77%). Ampicillin and chloramphenicol had little efficacy against Shigella flexneri (95.00 and 92.50% resistance). The percent resistance of Shigella sonnei strains to phosphomycin was elevated (44.69%). All strains studied were sensitive to colimycin and showed little resistance to the combination trimethoprim-sulfamethoxazol (16.42%).

摘要

对西班牙卡西斯市费尔南多·萨马科拉疗养院志贺氏菌病的发病率以及1979年分离出的94株宋内志贺氏菌和40株福氏志贺氏菌的抗生素敏感性进行了研究,并考虑了菌株对主要抗生素的耐药现状。检测到三次志贺氏菌病流行:一次在2月,由宋内志贺氏菌引起(16例),另外两次在8 - 9月和11月,由福氏志贺氏菌引起(43例和29例)。2至5岁儿童志贺氏菌感染发病率最高。几乎所有分离出的菌株都对磺胺类药物耐药(99.77%)。氨苄青霉素和氯霉素对福氏志贺氏菌疗效甚微(耐药率分别为95.00%和92.50%)。宋内志贺氏菌菌株对磷霉素的耐药率有所升高(44.69%)。所有研究的菌株对黏菌素敏感,对甲氧苄啶 - 磺胺甲恶唑合剂耐药性较低(16.42%)。

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