Shaw R G, Mashford M L, Desmond P V
Med J Aust. 1980 Nov 29;2(11):629-30. doi: 10.5694/j.1326-5377.1980.tb77073.x.
Three episodes, in which patients suffered a cardiac arrest in close association with receiving a bolus intravenous injection of cimetidine, are reported. The possible role of cimetidine in causing cardiac arrest, and the mechanisms which may be involved, are discussed. It is recommended that intravenous administration of cimetidine should be an infusion performed over at least 30 minutes.
本文报告了三例患者在静脉推注西咪替丁后不久即发生心脏骤停的病例。文中讨论了西咪替丁导致心脏骤停的可能作用及可能涉及的机制。建议静脉输注西咪替丁时应至少持续30分钟。