Amols H I, Kittell R, Paciotti M A, Hellend J A, Hogstrom K R, Collier M, Heller P
Med Phys. 1980 Nov-Dec;7(6):621-6. doi: 10.1118/1.594730.
Preliminary results on a system for delivering dynamic pion radiotherapy treatments are reported. The desired treatment volume is scanned across a small, focused pion beam using a computer-controlled treatment couch. A computer-controlled rangeshifting device modulates the stopping pion depth distribution in coordination with the couch motion to conform the dose to the shape of the treatment volume. For certain shaped tumors, the system can result in substantial normal tissue dose sparing and better field flatness as compared to irradiation by static treatments with broad terms. The characteristics of this new system, plus preliminary results for typical dose distributions as measured with thermoluminescent dosimeters (TLDs), are presented.
报告了一种用于提供动态π介子放射治疗的系统的初步结果。使用计算机控制的治疗床，在一个小的聚焦π介子束上扫描所需的治疗体积。计算机控制的射程移位装置与治疗床的运动协同调节π介子的停止深度分布，以使剂量符合治疗体积的形状。对于某些形状的肿瘤，与使用宽束静态治疗相比，该系统可以显著减少正常组织的剂量，并获得更好的射野平坦度。本文介绍了这种新系统的特点，以及用热释光剂量计（TLD）测量的典型剂量分布的初步结果。
