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意外宫内注射利多卡因后的胎儿心率变化

Fetal heart rate changes after accidental intrauterine lidocaine.

作者信息

Van Dorsten J P, Miller F C

出版信息

Obstet Gynecol. 1981 Feb;57(2):257-60.

PMID:7465134
Abstract

Fetal heart rate (FHR) decelerations resembling post-paracervical block (PCB) bradycardia were observed immediately after the inadvertent intrauterine injection of lidocaine hydrochloride. A review of the pathophysiology of post-PCB bradycardia is presented. The administration of a local anesthetic, either into the paracervical tissues or directly into the uterine cavity, may precipitate FHR decelerations principally, through arterial vasoconstriction with subsequent reflex responses and/or hypoxia in the fetus.

摘要

在意外子宫内注射盐酸利多卡因后,立即观察到类似宫颈旁阻滞(PCB)后心动过缓的胎儿心率(FHR)减速。本文综述了PCB后心动过缓的病理生理学。将局部麻醉剂注入宫颈旁组织或直接注入宫腔,可能主要通过动脉血管收缩及随后的反射反应和/或胎儿缺氧,导致FHR减速。

相似文献

1
Fetal heart rate changes after accidental intrauterine lidocaine.意外宫内注射利多卡因后的胎儿心率变化
Obstet Gynecol. 1981 Feb;57(2):257-60.
2
Post--paracervical block bradycardia: its prediction and preventability.
Am J Obstet Gynecol. 1976 Jul 1;125(5):665-7. doi: 10.1016/0002-9378(76)90790-0.
3
The effects of paracervical block on uterine activity and beat-to-beat variability of the fetal heart rate.
Am J Obstet Gynecol. 1978 Feb 1;130(3):284-8.
4
[The effect of paracervical block on the fetus].
Anaesthesist. 1972 Mar;21(3):91-4.
5
Spacing the injection interval with paracervical block: a randomized study.宫颈旁阻滞时注射间隔的调整:一项随机研究。
Obstet Gynecol. 1981 Dec;58(6):696-702.
6
Fetal heart rate and pH of fetal capillary blood during epidural analgesia in labor.分娩时硬膜外镇痛期间的胎儿心率及胎儿毛细血管血pH值
Obstet Gynecol. 1970 Dec;36(6):881-6.
7
Comparison of lidocaine and 2-chloroprocaine in paracervical block: clinical effects and drug concentrations in mother and child.利多卡因与2-氯普鲁卡因用于宫颈旁阻滞的比较:母婴的临床效果及药物浓度
Anesth Analg. 1983 Feb;62(2):168-73.
8
Maternal and fetal effects of low-dosage bupivacaine paracervical block.
J Perinat Med. 1984;12(2):75-84. doi: 10.1515/jpme.1984.12.2.75.
9
[Effects of local anesthetics on fetal heart rate patterns and neonatal neurobehavior].[局部麻醉药对胎儿心率模式及新生儿神经行为的影响]
Nihon Sanka Fujinka Gakkai Zasshi. 1985 Nov;37(11):2291-9.
10
Paracervical block anesthesia in obstetrics. 3. Choice of drug: fetal bradycardia following administration of lidocaine, mepivacaine, and prilocaine.
Am J Obstet Gynecol. 1973 Jun 1;116(3):320-5.

引用本文的文献

1
Adverse effects and drug interactions associated with local and regional anaesthesia.与局部和区域麻醉相关的不良反应及药物相互作用。
Drug Saf. 1998 Apr;18(4):221-50. doi: 10.2165/00002018-199818040-00001.