Van Dorsten J P, Miller F C, Yeh S Y
Obstet Gynecol. 1981 Dec;58(6):696-702.
To test the hypothesis that spacing the injection interval by 10 minutes would reduce the incidence of post-paracervical block bradycardia, 42 healthy subjects at low risk with normal fetal heart rate (FHR) patterns were included in a randomized trial. Twenty patients were given a conventional paracervical block (ie, almost simultaneous injection of the 2 sides), whereas 22 patients were given the second injection after a 10-minute interval. All patients were laterally positioned for 30 minutes before and 60 minutes after administration of the paracervical block. There were no cases of post-paracervical block bradycardia in either group, but a decrease in the baseline FHR of 5 beats per minute or more occurred in one half of each group. Both groups experienced significant decreases in the mean FHR. The authors conclude that patient selection and perhaps lateral positioning are more important than is spacing the injection interval. Furthermore, in properly selected subjects paracervical block offers simple, effective, and safe analgesia.
为验证将宫颈旁阻滞注射间隔延长10分钟会降低宫颈旁阻滞后心动过缓发生率这一假设,42名低风险、胎儿心率(FHR)模式正常的健康受试者被纳入一项随机试验。20例患者接受传统宫颈旁阻滞(即几乎同时注射两侧),而22例患者在间隔10分钟后进行第二次注射。所有患者在宫颈旁阻滞给药前30分钟和给药后60分钟均采取侧卧位。两组均未出现宫颈旁阻滞后心动过缓病例,但每组各有一半患者的基线FHR下降了5次/分钟或更多。两组的平均FHR均显著下降。作者得出结论,患者选择以及或许侧卧位比注射间隔更重要。此外,对于选择恰当的受试者,宫颈旁阻滞可提供简单、有效且安全的镇痛效果。