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自发性心绞痛中冠状动脉痉挛的诊断方法(作者译)

[An approach to the diagnosis of coronary artery spasm in spontaneous angina pectoris (author's transl)].

作者信息

Bory M, Benichou M, Sacerdote P, Egre M, Djiane P, Serradimigni A

出版信息

Nouv Presse Med. 1981 Jan 31;10(4):229-34.

PMID:7465358
Abstract

Spontaneously occurring spasms are more likely to be detected by performing coronary angiography during an acute ischaemic attack. This was achieved in 28 out of 41 cases. Spasm was found to be present in 23/25 attacks with elevated S-T segment but in only 5/16 attacks with other changes on ECG. The difference was statistically significant (p less than 0.01). When coronary angiography was performed outside anginal attacks, arterial spasm was detected in 16 out of 1071 cases (1.48%). The percentage increased in patients with spontaneous angina: 13/15 cases (8.6%). These spontaneous spasms are painless and can be differentiated from catheter-induced spasms and organic stenosis by the nitroglycerin test. Spasms which do not occur spontaneously can be provoked by methylergometrine maleate. This was done 175 time with 16 positive results. The criteria of positivity of the test, as well as its value, indications and dangers are discussed.

摘要

在急性缺血发作期间进行冠状动脉造影更有可能检测到自发性痉挛。41例中有28例实现了这一点。发现23/25例S-T段抬高的发作存在痉挛,但仅5/16例心电图有其他变化的发作存在痉挛。差异具有统计学意义(p小于0.01)。在非心绞痛发作期间进行冠状动脉造影时,1071例中有16例(1.48%)检测到动脉痉挛。自发性心绞痛患者的比例增加:13/15例(8.6%)。这些自发性痉挛是无痛的,通过硝酸甘油试验可与导管诱发的痉挛和器质性狭窄相鉴别。非自发性痉挛可由马来酸麦角新碱诱发。共进行了175次,其中16次呈阳性结果。讨论了该试验的阳性标准及其价值、适应证和风险。

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