用胆碱和丁苯那嗪治疗迟发性运动障碍。
Treatment of tardive dyskinesia with choline and tetrabenazine.
作者信息
Snell A P, Cleary M, Sambrook M
出版信息
Postgrad Med J. 1980 Sep;56(659):663-4. doi: 10.1136/pgmj.56.659.663.
Abstract
A patient with severe tardive dyskinesia due to long-term neuroleptic medication is described. The 2 factors immediately precipitating the onset of the disorder appeared to be the administration of benzhexol hydrochloride and the sudden termination of neuroleptic therapy. the disorder was satisfactorily controlled with choline chloride and a small dose of tetrabenazine. The suggested mechanism of tardive dyskinesia is discussed.
摘要
本文描述了一名因长期服用抗精神病药物而患有严重迟发性运动障碍的患者。导致该疾病发作的两个直接因素似乎是盐酸苯海索的使用和抗精神病药物治疗的突然终止。该疾病通过氯化胆碱和小剂量的丁苯那嗪得到了满意的控制。文中还讨论了迟发性运动障碍的可能机制。
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本文引用的文献
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Treatment of tardive dyskinesia. I. Clinical efficacy of a dopamine-depleting agent, tetrabenazine.
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Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study.胆碱和卵磷脂治疗迟发性运动障碍：一项初步研究的初步结果。
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Tardive dyskinesia and antiparkinsonian medication.迟发性运动障碍与抗帕金森病药物
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