迟发性运动障碍的治疗：使用丁苯那嗪的初步报告

Treatment of tardive dyskinesia: preliminary report on use of tetrabenazine.

作者信息

Watson M W, Skelton D, Jamali F

机构信息

Mentally Dysfunctioning Elderly Unit, Edmonton Rural Auxiliary Hospital and Nursing Home, Alberta.

出版信息

Can J Psychiatry. 1988 Feb;33(1):11-3. doi: 10.1177/070674378803300104.

DOI:10.1177/070674378803300104

PMID:2965967

Abstract

Tetrabenazine has been used for treatment of tardive dyskinesia sporadically over the past twenty years. Dose has usually been decided empirically without assaying blood levels. This report describes 23 cases treated successfully with tetrabenazine. Our method of measuring levels of tetrabenazine and its metabolites in biological samples is described briefly.

摘要

在过去二十年中，丁苯那嗪偶尔被用于治疗迟发性运动障碍。剂量通常凭经验确定，而不检测血药浓度。本报告描述了23例用丁苯那嗪成功治疗的病例。简要介绍了我们测量生物样品中丁苯那嗪及其代谢物水平的方法。