Constantinou C E
Urol Int. 1978;33(6):399-416. doi: 10.1159/000280229.
The patterns of mechanical contractility in the pyeloureteral pacemaker system were explored in an effort to identify some of the properties of initiating ureteral peristalsis. Rabbit renal pelvises were studied in vivo, in vitro perfused with Krebs solution through the renal artery and in segments. The results show that all segments of renal pelvic smooth muscle are capable of spontaneous contractions, the fornix having the highest frequency with respect to the pelvis. It is also demonstrated that the pelvic contractile wave concentrically accelerates along the renal pelvic perimeter. Under steady state conditions, renal pelvic pressure undergoes a low frequency oscillation having a period of 1--2 min which is flow-rate dependent. The results are discussed within the context of the pyeloureteral pacemaker system and the possible existence of a feedback mechanisms between the renal pelvis and the perfusion of the kidney.
为了确定启动输尿管蠕动的一些特性，对肾盂输尿管起搏器系统中的机械收缩模式进行了研究。对兔肾盂进行了体内研究、通过肾动脉用 Krebs 溶液进行体外灌注研究以及分段研究。结果表明，肾盂平滑肌的所有节段都能够自发收缩，穹窿部相对于肾盂具有最高的频率。还证明了肾盂收缩波沿肾盂周边呈同心加速。在稳态条件下，肾盂压力会经历低频振荡，其周期为 1 - 2 分钟，且与流速有关。在肾盂输尿管起搏器系统的背景下以及肾盂与肾脏灌注之间可能存在反馈机制的情况下对结果进行了讨论。
