Rodriguez E, Reynolds G W, Thompson J A
Science. 1981 Mar 27;211(4489):1444-5. doi: 10.1126/science.7466403.
Chemical and dermatotoxicological investigations of the natural and processed resin of the Mexican rubber plant, guayule (Parthenium argentatum), has established the presence of a sesquiterpene cinnamic acid ester (guayulin A) that is a potent elicitor of allergic contact dermatitis in experimental animals. The guayule contact allergen is comparable to the poison ivy skin allergens as an elicitor of dermatitis in sensitized guinea pigs.
对墨西哥橡胶植物银胶菊（Parthenium argentatum）的天然树脂和加工树脂进行的化学及皮肤毒理学研究表明，其中存在一种倍半萜肉桂酸酯（银胶菊素A），它是实验动物过敏性接触性皮炎的强效诱导剂。在致敏豚鼠中，银胶菊接触性变应原作为皮炎诱导剂，与毒葛皮肤变应原相当。
