Sasaki M, Looman B, Terasaki P I
Tissue Antigens. 1980 Mar;15(3):225-30. doi: 10.1111/j.1399-0039.1980.tb00911.x.
The ADCC test has been miniaturized to use 0.05 ml of whole blood per test as ADCC effectors. A linear dose response was shown by dilutions of 0.05 ml of blood down to a 1:16 dilution. ADCC effector activities of 40 patients with lung cancer and four with leukemia were markedly less than the activity of 200 normal subjects. Melanoma patients did not have comparable statistically significant loss of ADCC activity.
ADCC试验已小型化,每次试验使用0.05毫升全血作为ADCC效应细胞。从0.05毫升血液稀释至1:16稀释度呈线性剂量反应。40例肺癌患者和4例白血病患者的ADCC效应细胞活性明显低于200例正常受试者的活性。黑色素瘤患者的ADCC活性没有统计学上可比的显著降低。