Lal S, Gupta S K, Chandra S V
Toxicol Lett. 1980 Mar;5(3-4):203-6. doi: 10.1016/0378-4274(80)90060-0.
Manganese chloride was administered alone or in combination with zinc chloride, mercuric chloride and cadmium chloride i.p. to rats for 30 days to investigate the effect of interaction of these elements on their content in brain, liver and kidney. Significant changes in the accumulation of these metals after combined exposure indicated that metabolic interactions occur. Alterations in the tissue contents of manganese, zinc, mercury and cadmium after combined administration may reflect changes at the absorptive sites or in excretory pattern.
将氯化锰单独或与氯化锌、氯化汞和氯化镉联合腹腔注射给大鼠30天，以研究这些元素之间的相互作用对其在脑、肝和肾中含量的影响。联合暴露后这些金属积累的显著变化表明发生了代谢相互作用。联合给药后锰、锌、汞和镉的组织含量变化可能反映了吸收部位或排泄模式的变化。
