Klinkmann H, Schmicker R
Z Gesamte Inn Med. 1980 Aug 15;35(16):suppl 58-64.
The three main points of the conservative therapy of the chronic renal insufficiency are the treatment of the basic disease, the dietary therapy and the symptomatic medicamentous measures. The possibilities of treatment of the basic disease, however, are restricted in advanced renal insufficiency, but they may reduce the progression of the nephropathy. Decisive for the success of the conservative therapy are the dietary measures, in which case the restriction of the quantity of proteins with consideration of the biological value, the caloric intake of at last 35 Cal/kg body weight/day and the equalized fluid balance must be particularly emphasized. The different possibilities of the protein restriction and possibilities of control of the protein metabolism are explained. Depending on the degree of the chronic renal insufficiency and the present clinical symptomatology symptomatic medicamentous measures are used. Following in indications for the beginning of the therapy of dialysis it is referred to the importance of the system of renal dispensaries for the optimum performance of the conservative therapy.
慢性肾功能不全保守治疗的三个主要要点是基础疾病的治疗、饮食疗法和对症药物治疗措施。然而,在晚期肾功能不全中,基础疾病的治疗可能性受到限制,但它们可能会减缓肾病的进展。保守治疗成功的关键在于饮食措施,在这种情况下,必须特别强调考虑生物价值限制蛋白质摄入量、至少35千卡/千克体重/天的热量摄入以及平衡的液体平衡。文中解释了蛋白质限制的不同可能性以及蛋白质代谢的控制方法。根据慢性肾功能不全的程度和当前临床症状采用对症药物治疗措施。在提及透析治疗开始的指征之后,还提到了肾脏诊疗体系对于保守治疗最佳效果的重要性。