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[中脑网状结构优势灶对运动分析器功能状态的影响]

[Effect of a dominant focus in the midbrain reticular formation on the functional state of the motor analyzer].

作者信息

Grechushnikova L S

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1980 Nov-Dec;30(6):1272-8.

PMID:7467849
Abstract

In chronic experiments on rabbits it was shown that after two-three stimulations of the midbrain reticular formation (stimulation frequency 200 cps, pulse duration 0.1-0.5 ms, voltage 1-3 V, stimulation duration 5 s) a dominant focus was formed in it, which led simultaneously to a statistically significant increase in the amplitude of evoked potential in the sensorimotor cerebral cortex and in motor reactions to afferent stimuli (light, sound). The state of increased excitability persisted for a long time (10-30 days depending on the number of stimulations of the reticular formation). Multiple stimulation of the reticular formation (5-12 times) led to creation of a pathological defensive dominant, manifested in a unitype series of legs movements in response to light and sound stimuli.

摘要

在对兔子进行的慢性实验中发现,在对中脑网状结构进行两到三次刺激后(刺激频率200 cps,脉冲持续时间0.1 - 0.5毫秒,电压1 - 3伏,刺激持续时间5秒),其中形成了一个优势灶,这同时导致感觉运动皮层诱发电位的幅度以及对传入刺激(光、声)的运动反应在统计学上显著增加。兴奋性增强的状态持续了很长时间(10 - 30天,取决于对网状结构的刺激次数)。对网状结构进行多次刺激(5 - 12次)导致形成病理性防御优势,表现为对光和声刺激做出单一类型的腿部运动系列反应。

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