Aĭrapetian A A, Gevorkian O V
Zh Evol Biokhim Fiziol. 1977 May-Jun;13(3):391-7.
High frequency stimulation of the mesencephalic reticular formation produces significant inhibition of neuronal activity in the sensorimotor cortex, the effect being equally observed in both hemispheres. In case of low frequency stimulation, marked difference was observed between the reaction of ipsi- and contralateral neurons. Under these conditions, contralateral neurons produce mainly facilitation responses. In both hemispheres evident predominance of tonic effects was observed which revealed itself in the continuation of the reaction in the poststimulation period. Single shocks applied to the midbrain reticular formation elicited in the cortex the evoked potentials of two types: one with a constant and the other with varying latent periods. The former exhibited a latency of 4-18 msec. Responses with varying latencies were predominant. In general, latent periods were longer in contralateral hemisphere.
高频刺激中脑网状结构会显著抑制感觉运动皮层中的神经元活动,这种效应在两个半球均能观察到。在低频刺激的情况下,同侧和对侧神经元的反应存在明显差异。在这些条件下,对侧神经元主要产生易化反应。在两个半球均观察到明显的强直效应优势,这在刺激后时期反应的持续中表现出来。对中脑网状结构施加单次电击可在皮层诱发两种类型的诱发电位:一种潜伏期恒定,另一种潜伏期可变。前者的潜伏期为4 - 18毫秒。潜伏期可变的反应占主导。一般来说,对侧半球的潜伏期更长。