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[使用³H-胸腺嘧啶核苷的体外放射自显影术对磨损材料的适用性(作者译)]

[Applicability to abrasion material of in vitro autoradiography, using 3H-thymidine (author's transl)].

作者信息

Theuring F, Erbstösser E, Erbstösser R, Link M

出版信息

Zentralbl Gynakol. 1980;102(19):1125-30.

PMID:7467953
Abstract

The applicability of in vitro autoradiography, using 3H-thymidine, was tested on material obtained from gynaecological abrasion. Included were 161 abrasion samples obtained from 151 patients, and 88 per cent of them proved evaluable by autoradiography. The use of in vitro autoradiography was found to give no additional gain in information for biological assessment. Index testing by means of in vitro autoradiography failed to prove worthwhile unless it came to examination of polyps or of glandular-cystic hyperplasia or of effects exerted on the endometrium by ovarian tumours with sizeable hormonal activity. Endometrium was found to be a kind of tissue characterised in both intact and pathological condition by pronounced individual age-dependent and cycledependent variations of its marking indices.

摘要

利用³H-胸腺嘧啶核苷的体外放射自显影技术在妇科刮取物上进行了适用性测试。其中包含从151名患者处获取的161份刮取物样本,其中88%的样本经放射自显影可进行评估。结果发现,体外放射自显影技术在生物学评估方面并未提供更多的信息。除非是对息肉、腺囊性增生或具有显著激素活性的卵巢肿瘤对子宫内膜的影响进行检查,否则通过体外放射自显影进行指标检测并不值得。研究发现,子宫内膜是一种组织,其标记指数在完整和病理状态下均具有明显的个体年龄依赖性和周期依赖性变化。

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