Lee K, Nielsen J D, Zeeberg I, Gormsen J
Acta Neurol Scand. 1980 Nov;62(5):287-92. doi: 10.1111/j.1600-0404.1980.tb03038.x.
Alcoholism has been shown to predispose to cerebrovascular thrombosis in normotensive males under the age of 50. To elucidate this phenomenon platelet aggregation and fibrinolytic activity were studied in 29 alcoholic males under 50 years of age who showed no evidence of acute cerebrovascular disease. Age matched healthy nonalcoholic volunteers made up the control population. Platelet aggregation did not differ significantly (P greater than 0.05) in the two groups. Fibrinolytic activity was significantly reduced in the alcoholics as compared to the controls (P = 0.005). The data suggest that the alcoholics have an increased thrombotic tendency. This may cause alcoholics to be at a greater risk of suffering stroke at an early age.
研究表明，50岁以下的血压正常男性中，酗酒易引发脑血管血栓形成。为阐明这一现象，对29名50岁以下无急性脑血管疾病迹象的男性酗酒者进行了血小板聚集和纤溶活性研究。年龄匹配的健康非酗酒志愿者组成了对照组。两组的血小板聚集无显著差异（P大于0.05）。与对照组相比，酗酒者的纤溶活性显著降低（P = 0.005）。数据表明，酗酒者的血栓形成倾向增加。这可能使酗酒者在早年患中风的风险更高。
