Bansal B C, Prakash C, Arya R K, Gulati S K, Mittal S C
Stroke. 1978 Mar-Apr;9(2):137-9. doi: 10.1161/01.str.9.2.137.
Fifty patients with occlusive cerebrovascular disease (ischemic thrombotic cerebrovascular disease--ITCBVC) were studied for clinical features, angiographic findings, serum lipids, platelet functions and fibrinolytic activity. Angiograms were abnormal in 24 of 36 cases. Two-thirds of these had an abnormality of the internal carotid artery in the neck; one-third had occlusion of the middle and/or anterior cerebral arteries. A statistically significant rise of serum triglycerides, pre-beta lipoproteins, platelet adhesiveness and aggregation, and a decrease in fibrinolytic activity were noticed in these patients as compared to age and sex matched controls. The correlation coefficient did not show any intercorrelation between the platelet adhesiveness and raised lipid fractions. These factors could be responsible for the atheroma resulting in large vessel occlusion.
对50例闭塞性脑血管疾病（缺血性血栓性脑血管疾病——ITCBVC）患者进行了临床特征、血管造影结果、血脂、血小板功能和纤溶活性的研究。36例患者中24例血管造影异常。其中三分之二患者颈部颈内动脉异常；三分之一患者大脑中动脉和/或大脑前动脉闭塞。与年龄和性别匹配的对照组相比，这些患者血清甘油三酯、前β脂蛋白、血小板黏附性和聚集性有统计学意义的升高，纤溶活性降低。血小板黏附性与升高的脂质成分之间的相关系数未显示任何相互关系。这些因素可能是导致大血管闭塞的动脉粥样硬化的原因。
