Bech P, Gram L F, Reisby N, Rafaelsen O J
Acta Psychiatr Scand. 1980 Aug;62(2):140-53. doi: 10.1111/j.1600-0447.1980.tb00601.x.
The WHO (World Health Organization) Depression Scale is a new rating scale developed to evaluate the complete clinical history and description of depression. Items of the WHO scale were transformed to cover the items of the two Newcastle scales that are designed to differentiate between endogenous and non-endogenous depressions. In 98 depressed inpatients examined prior to antidepressive therapy only moderate agreement between scores transformed to the two Newcastle scales was found. Also the distribution patterns of the scores on the two scales were different. In patients classified as endogenous on one or both scales a significant relationship between plasma levels of imipramine or clomipramine and antidepressive effect was found. In patients classified on both scales as doubtful - or non-endogenous depressions - no such correlation could be identified. The initial severity of depression, as defined by the Hamilton Depression Scale, was the same in endogenous, doubtful and non-endogenous depression according to the scores transformed to the two Newcastle scales.
世界卫生组织抑郁量表是一种新开发的评定量表，用于评估抑郁症的完整临床病史和描述。世界卫生组织量表的项目经过转换，以涵盖两个纽卡斯尔量表的项目，这两个量表旨在区分内源性和非内源性抑郁症。在98例接受抗抑郁治疗前检查的抑郁症住院患者中，发现转换为两个纽卡斯尔量表后的分数之间只有中等程度的一致性。此外，两个量表上分数的分布模式也不同。在一个或两个量表上被归类为内源性的患者中，发现丙咪嗪或氯米帕明的血浆水平与抗抑郁效果之间存在显著关系。在两个量表上都被归类为可疑或非内源性抑郁症的患者中，未发现这种相关性。根据转换为两个纽卡斯尔量表后的分数，根据汉密尔顿抑郁量表定义的抑郁症初始严重程度在内源性、可疑和非内源性抑郁症中是相同的。
