Smith F R, Rogers A I
Am J Gastroenterol. 1980 Sep;74(3):282-4.
A case of vasoactive intestinal peptide-producing adenoma of the tail of the pancreas (VIP) successfully managed by surgical resection is presented. Peripheral venous VIP levels correlated with the severity of the diarrhea. Intraoperatively, the VIP levels in the splenic and portal veins were 485 and 100 pg./ml., respectively. These data suggest that preoperative selective transhepatic venous catheterization for VIP sampling might be used to establish the site of VIP production and, thereby, direct surgical management. This technic requires further evaluation regarding its role in this clinical setting.
本文报告一例通过手术切除成功治疗的胰腺尾部血管活性肠肽瘤（VIP瘤）。外周静脉血中VIP水平与腹泻严重程度相关。术中，脾静脉和门静脉中的VIP水平分别为485和100 pg/ml。这些数据表明，术前选择性经肝静脉插管采集VIP样本可用于确定VIP的产生部位，从而指导手术治疗。这项技术在这种临床情况下的作用需要进一步评估。
