Saetersdal T, Rotevatn S, Myklebust R, Odegården S
Anat Embryol (Berl). 1980;160(1):1-9. doi: 10.1007/BF00315645.
Atrial specific granules first appear in the human auricle by about 7 weeks of fetal development. They are rapidly formed between the 7 and 8 week stages. Granules are fairly evenly spread at the onset of their appearance. As they increase in number they soon aggregate in the juxtanuclear and subsarcolemmal positions. The electron dense matrix of granules of young cardiomyoblasts is condensed and/or synthesized within the Golgi cisternae. Large and electron dense cisternae are sometimes observed in close connection with mature specific granules. Bristle coated vesicles develop by a "budding off" process from the lateral margins of the Golgi cisternae. A fusion between bristle coated vesicles and specific granules is indicated.
心房特异性颗粒在胎儿发育约7周时首次出现在人耳中。它们在7至8周阶段迅速形成。颗粒在出现时分布相当均匀。随着数量增加，它们很快聚集在核周和肌膜下位置。年轻心肌母细胞颗粒的电子致密基质在高尔基池内浓缩和/或合成。有时观察到大型电子致密池与成熟的特异性颗粒紧密相连。有被小泡通过从高尔基池的侧缘“出芽”过程形成。显示有被小泡与特异性颗粒之间存在融合。
