Babin R W, Fratkin J, Harker L A
Arch Otolaryngol. 1981 Jan;107(1):55-8. doi: 10.1001/archotol.1981.00790370057013.
The temporal bones in two patients contained asymptomatic neuromas of the facial nerve and a third patient had an identical tumor of the chorda tympani. All three neuromas occurred in the presence of chronic inflammatory middle ear disease. Histologically all three resembled traumatic (repairative) neuromas. Both of the facial nerve lesions occurred at a site of frequent fallopian canal dehiscence. It is suggested that occasionally, long-term exposure to the facial nerve to chronic inflammation results in proliferation of neurofibrils leading to neuroma formation.
两名患者的颞骨中含有无症状的面神经神经瘤,第三名患者患有相同的鼓索神经瘤。所有这三个神经瘤均在慢性炎症性中耳疾病存在的情况下发生。组织学上,这三个神经瘤均类似于创伤性(修复性)神经瘤。两个面神经病变均发生在面神经管经常裂开的部位。有人提出,偶尔长期暴露于慢性炎症中的面神经会导致神经原纤维增殖,从而导致神经瘤形成。