鼠源巨噬细胞样细胞系的溶酶体酶自发分泌
Spontaneous lysosomal enzyme secretion by a murine macrophage-like cell line.
作者信息
Jessup W, Dean R T
出版信息
Biochem J. 1980 Sep 15;190(3):847-50. doi: 10.1042/bj1900847.
Abstract
Lysosomal enzyme secretion by the murine macrophage-like cell line, P388D1, was compared with that of normal peritoneal macrophages. Unlike macrophages, lysosomal hydrolase secretion by P388D1 cells occurred spontaneously in vitro and was not further stimulated by the presentation of inflammatory agents such as zymosan and asbestos.
摘要
将小鼠巨噬细胞样细胞系P388D1的溶酶体酶分泌与正常腹膜巨噬细胞的溶酶体酶分泌进行了比较。与巨噬细胞不同，P388D1细胞的溶酶体水解酶分泌在体外是自发发生的，并且不会因诸如酵母聚糖和石棉等炎症因子的存在而进一步受到刺激。
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本文引用的文献
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In vitro synthesis and secretion of lysozyme by mononuclear phagocytes.单核吞噬细胞体外合成与分泌溶菌酶
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Asbestos induces selective release of lysosomal enzymes from mononuclear phagocytes.石棉会诱导单核吞噬细胞选择性释放溶酶体酶。
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Identification of macrophage-like characteristics in a cultured murine tumor line.在一种培养的小鼠肿瘤细胞系中鉴定巨噬细胞样特征。
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Biologic and biochemical activities of continuous macrophage cell lines P388D1 and J774.1.连续巨噬细胞系P388D1和J774.1的生物学和生化活性
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