Maass H, Jonat W, Stolzenbach G, Trams G
Cancer. 1980 Dec 15;46(12 Suppl):2835-7. doi: 10.1002/1097-0142(19801215)46:12+<2835::aid-cncr2820461420>3.0.co;2-m.
Patients with advanced breast cancer and low or poor concentration of estrogen receptors in tumor biopsies have little chance of responding to endocrine therapy. This problem was seen in a group of nonresponding estrogen receptor-positive (ER+) patients. Some comments on possible explanations for this phenomenon are made and suggestions to overcome it are given.
患有晚期乳腺癌且肿瘤活检中雌激素受体浓度低或水平差的患者对内分泌治疗反应的机会很小。在一组无反应的雌激素受体阳性(ER+)患者中出现了这个问题。针对这一现象的可能解释进行了一些评论,并给出了克服它的建议。