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[生物假体在儿童和青少年心脏瓣膜置换中的应用]

[Use of biological prostheses for cardiac valve replacement in children and adolescents].

作者信息

Covino E, Tecchia L B, Formicola V, Romano M, Lino R

出版信息

Boll Soc Ital Biol Sper. 1980 Dec 30;56(24):2612-8.

PMID:7470308
Abstract

Between January 1976 and June 1980 a consecutive series of 13 patients aging from 9 to 18 years underwent cardiac valve replacement, out of 590 valve replacement operations. All had rheumatic heart disease and many had severe cardiac symptoms; all underwent cardiac catheterization and angiography before operation. Ten single valve replacements, 7 in the aortic, and 3 in the mitral position, and 3 double valve replacements were performed. All patients survived operation, except the one who died 2 months later for congestive heart failure. The others have been followed from 1 to 47 months, averaging 20,5 months. All are free of cardiac symptoms and are being treated with antirheumatic drugs. They are not anticoagulated after 6 months. The operative mortality is low in our bioprosthetic valve replacement, and we think that these operations are safely feasible.

摘要

在1976年1月至1980年6月期间,在590例心脏瓣膜置换手术中,连续有13例年龄在9至18岁的患者接受了心脏瓣膜置换。所有患者均患有风湿性心脏病,许多患者有严重的心脏症状;所有患者在手术前均接受了心导管检查和血管造影。进行了10例单瓣膜置换,其中7例为主动脉瓣置换,3例为二尖瓣置换,以及3例双瓣膜置换。除1例术后2个月因充血性心力衰竭死亡外,所有患者均存活。其他患者随访了1至47个月,平均20.5个月。所有患者均无心脏症状,正在接受抗风湿药物治疗。6个月后不再进行抗凝治疗。我们的生物瓣膜置换手术死亡率较低,我们认为这些手术安全可行。

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