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儿童和青少年的瓣膜置换术。

Valve replacement in children and adolescents.

作者信息

Mathews R A, Park S C, Neches W H, Lenox C C, Zuberbuhler J R, Fricker F J, Siewers R D, Hardesty R L, Lerberg D B, Bahnson H T

出版信息

J Thorac Cardiovasc Surg. 1977 Jun;73(6):872-6.

PMID:870765
Abstract

Replacement of diseased heart valves has become the treatment of choice in many adults. Valve replacement in older children and adolescents has been done in our institution only when other procedures are ineffective. Over the past 10 years, 24 patients have received 28 artificial valves. Thirteen (54 per cent) had rheumatic heart disease; the remainder had congenital or acquired valvular abnormalities. The Björk-Shiley valve was most commonly used in the aortic position and the Beall prosthesis in the mitral position. Sixteen patients (67 per cent) survived operation and have been followed from 3 to 79 months, averaging 27 months. All are free of cardiac symptoms. Hemarthrosis occurred once in 2 survivors (13 per cent). Eight patients died (33 per cent), 5 immediately postoperatively and 3 within a year after the operation. The mortality rate has declined to 21 percent during the past 3 years. Our experience in the pediatric age group suggests that valve replacement is a serious undertaking with higher mortality rate than in adults. The operation should be reserved for those patients in whom valvuloplasty or valvulotomy is expected to be ineffective.

摘要

置换病变的心脏瓣膜已成为许多成年人的首选治疗方法。在我们机构,只有当其他手术无效时,才会对大龄儿童和青少年进行瓣膜置换。在过去10年中,24例患者接受了28个人工瓣膜。13例(54%)患有风湿性心脏病;其余患者有先天性或后天性瓣膜异常。Björk-Shiley瓣膜最常用于主动脉位置,而Beall人工瓣膜用于二尖瓣位置。16例患者(67%)术后存活,随访时间为3至79个月,平均27个月。所有患者均无心脏症状。2例存活患者(13%)发生过一次关节积血。8例患者死亡(33%),5例术后立即死亡,3例在术后一年内死亡。在过去3年中,死亡率已降至21%。我们在儿童年龄组的经验表明,瓣膜置换是一项严肃的手术,死亡率高于成年人。该手术应仅用于那些预计瓣膜成形术或瓣膜切开术无效的患者。

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