Hakama M, Penttinen J
Br J Obstet Gynaecol. 1981 Mar;88(3):209-14. doi: 10.1111/j.1471-0528.1981.tb00970.x.
Incidence rates for cervical cancer were analyzed for Finland in 1953 to 1974. The age-specific incidence rates fit an age-incidence curve based on the assumption of two epidemiological components. The time trends give support to the hypothesis that one of the components occurs at a lower age and is preceded by a carcinoma in situ stage. The risk of cervical cancer originating from the component occurring in younger women showed a decreasing trend which correlated with the organized mass screening programme. The other component occurred later in life and was not influenced by the screening programme. It was estimated that the proportion of the cases in the earlier category decreased from 53% in the 1950s to 17% in 1973 to 1974 of all cases of cervical cancer diagnosed in the Finnish population.
对芬兰1953年至1974年期间宫颈癌的发病率进行了分析。特定年龄发病率符合基于两种流行病学成分假设的年龄发病率曲线。时间趋势支持这样一种假设，即其中一种成分发生在较低年龄，且之前有原位癌阶段。源自年轻女性中出现的成分的宫颈癌风险呈下降趋势，这与有组织的大规模筛查计划相关。另一种成分出现在生命后期，不受筛查计划的影响。据估计，在芬兰人群中诊断出的所有宫颈癌病例中，早期类别病例的比例从20世纪50年代的53%降至1973年至1974年的17%。
