Korogodin D V, Poverennyĭ A M
Biull Eksp Biol Med. 1980 Dec;90(12):706-7.
Interaction of acid-soluble collagen and C1a component of complement with nucleic acids (NA) is defined by their polyanionic properties. Occurrence of the exocyclic amino group in the structure of nitrous bases from which polynucleotides are made up inhibits their interaction with the proteins are made up inhibits their interaction with the proteins even when this group is within the double helix. This takes place during the formation of the hybrid molecule poly I-poly C. It is assumed that the collagen-like part of C1q greatly contributes to its interaction with nucleic acids.
酸溶性胶原蛋白与补体C1a成分和核酸（NA）的相互作用由它们的聚阴离子特性决定。构成多核苷酸的亚硝碱基结构中环外氨基的存在会抑制其与蛋白质的相互作用，即使该基团位于双螺旋内部也是如此。这在多聚肌苷酸-多聚胞苷酸杂交分子形成过程中发生。据推测，C1q的胶原样部分对其与核酸的相互作用有很大贡献。
