Cuschieri A, Hutchinson F, Neil G D, Wisbey M L, Wood R A, Preece P, Clark J
Br J Surg. 1981 Mar;68(3):147-9. doi: 10.1002/bjs.1800680303.
In this blind prospective study of breast scintiscanning with 99Tcm-diethylene triamine penta-acetic acid (DTPA) in 67 female patients presenting at a primary breast referral clinic, we have observed that this investigation has a high diagnostic accuracy in distinguishing benign from malignant lesions of the breast. The predictive value of the test when positive in establishing the presence of cancer is 94 per cent with a false negative rate of 6 per cent. The predictive value of the test when negative in excluding cancer in 97 per cent with a false positive rate of 3 per cent. Initial studies also indicate the potential value of DTPA breast scintiscanning in delineating the activity of painful benign lesions of the breast.
在这项对67名到初级乳腺转诊诊所就诊的女性患者进行的99锝-二乙三胺五乙酸（DTPA）乳腺闪烁扫描的前瞻性盲法研究中，我们观察到该检查在区分乳腺良性和恶性病变方面具有较高的诊断准确性。该检查呈阳性时诊断癌症的预测值为94%，假阴性率为6%。该检查呈阴性时排除癌症的预测值为97%，假阳性率为3%。初步研究还表明，DTPA乳腺闪烁扫描在描绘乳腺疼痛性良性病变的活性方面具有潜在价值。
