氟尿嘧啶与甲环亚硝脲治疗晚期消化道癌
[Treatment of advanced digestive cancer with fluorouracil and methyl-CCNU].
作者信息
Fleischer I, Wainstein R, Jovtis S, Colombato L O
出版信息
Acta Gastroenterol Latinoam. 1978;8(3):191-3.
PMID:747086
Abstract
We relate the experience obtained by treatment of 20 advanced digestive cancer patients, with the association of 5 fluorouracil and methyl-C.C.N.U. Objective response was found in 4 patients (20%). Toxicity consisted of leucopenia in 3 patients, allergic phenomena in 2 and diarrhea in 1 patient. Mean survival is increased in 3 months in responders, when compared with non-responders, although this difference has not statistical value.
摘要
我们讲述了对20例晚期消化道癌症患者采用5-氟尿嘧啶与甲基环己亚硝脲联合治疗所获得的经验。4例患者（20%）出现客观缓解。毒性反应包括3例患者出现白细胞减少，2例出现过敏现象，1例出现腹泻。与未缓解者相比，缓解者的平均生存期延长了3个月，尽管这种差异无统计学意义。
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