Caddy K W, Sidman R L, Eicher E M
Brain Res. 1981 Mar 9;208(1):251-5. doi: 10.1016/0006-8993(81)90643-0.
A new mutant mouse named Stumbler (stu) displays clinical features suggesting a cerebellar lesion. The main light microscopic findings, based on a Golgi technique and on sections of plastic embedded material, are that Purkinje cells in the mutant cerebellum have small dendritic arborizations and exhibit immature spines on their somata. Purkinje cells also contain an increased number of mitochondrial profiles both in cell bodies and in swellings on dendrites.
一种名为“蹒跚者”（stu）的新突变小鼠表现出提示小脑病变的临床特征。基于高尔基技术和塑料包埋材料切片的主要光学显微镜观察结果是，突变小鼠小脑中的浦肯野细胞具有小的树突分支，并且其胞体上呈现未成熟的棘突。浦肯野细胞的细胞体和树突肿胀处的线粒体轮廓数量也增加。
