贝克抗叶酸制剂用于转移性肾细胞癌的II期试验：一项西南肿瘤协作组研究
Phase II trial of Baker's antifol in metastatic renal cell carcinoma: a Southwest Oncology Group Study.
作者信息
Bukowski R M, LoBuglio A, McCracken J, Pugh R
出版信息
Cancer Treat Rep. 1980;64(12):1387-8.
PMID:7471126
Abstract
Fifteen patients with metastatic renal cell carcinoma were treated with Baker's antifol at a dose schedule of 250 mg/m2 iv for 3 days every 3 weeks. One objective response was seen, and toxicity was minimal. No usefulness of Baker's antifol in the treatment of metastatic renal cell carcinoma was demonstrated.
摘要
15例转移性肾细胞癌患者接受了贝克抗叶酸制剂治疗，给药方案为每3周静脉注射250mg/m²，共3天。观察到1例客观缓解，且毒性极小。未证明贝克抗叶酸制剂对转移性肾细胞癌治疗有效。
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