贝克抗叶酸制剂用于转移性肾细胞癌的II期试验：一项西南肿瘤协作组研究
Phase II trial of Baker's antifol in metastatic renal cell carcinoma: a Southwest Oncology Group Study.
作者信息
Bukowski R M, LoBuglio A, McCracken J, Pugh R
出版信息
Cancer Treat Rep. 1980;64(12):1387-8.
PMID:7471126
Abstract
Fifteen patients with metastatic renal cell carcinoma were treated with Baker's antifol at a dose schedule of 250 mg/m2 iv for 3 days every 3 weeks. One objective response was seen, and toxicity was minimal. No usefulness of Baker's antifol in the treatment of metastatic renal cell carcinoma was demonstrated.
摘要
15例转移性肾细胞癌患者接受了贝克抗叶酸制剂治疗，给药方案为每3周静脉注射250mg/m²，共3天。观察到1例客观缓解，且毒性极小。未证明贝克抗叶酸制剂对转移性肾细胞癌治疗有效。
相似文献
1
Phase II trial of Baker's antifol in metastatic renal cell carcinoma: a Southwest Oncology Group Study.贝克抗叶酸制剂用于转移性肾细胞癌的II期试验：一项西南肿瘤协作组研究
Cancer Treat Rep. 1980;64(12):1387-8.
2
Phase II trial of Baker's antifol in metastatic sarcoma.贝克抗叶酸剂用于转移性肉瘤的II期试验。
Cancer Treat Rep. 1977 Nov;61(8):1485-7.
3
Phase 2 study with Baker's Antifol in solid tumors.使用贝克氏抗叶酸剂治疗实体瘤的2期研究。
Cancer Res. 1977 Apr;37(4):980-3.
4
5
6
Phase II trial of Baker's antifol in patients with recurrent or inoperable head and neck cancer.
Cancer Treat Rep. 1986 Aug;70(8):1039-40.
7
Phase II trial of methyl-G (methylglyoxal bis-guanylhydrazone) in patients with metastatic renal cell carcinoma.
Cancer Clin Trials. 1981 Winter;4(4):411-4.
8
9
Phase II study of Baker's antifol in advanced colorectal cancer.贝克抗叶酸剂用于晚期结直肠癌的II期研究。
Cancer Treat Rep. 1978 Apr;62(4):553-4.
10
Phase I--II trial of methyl-GAG in the treatment of patients with metastatic renal adenocarcinoma.甲基葡糖胺聚糖治疗转移性肾腺癌患者的I-II期试验
Cancer Treat Rep. 1981 Jan-Feb;65(1-2):17-20.
Zotero 插件