Holdstock G, Mitchell J R
Lancet. 1977;2(8052-8053):1314-6. doi: 10.1016/s0140-6736(77)90365-8.
The erythrocyte-sedimentation rate (E.S.R.) was measured before and after in-vitro defibrination in 107 patients with high E.S.R.S. The reduction in E.S.R. on defibrination correlates with the fibrinogen level while the post-defibrination E.S.R. correlates with the globulin level. The ratio between the post-defibrination E.S.R. and the pre-defibrination, or standard, E.S.R. varies with different diseases; it is highest when an excess of globulins is the cause of the high E.S.R. and lowest when there is an excess of fibrinogen. Measurement of the post-fibrination E.S.R. is quick and easy and may help in the initial investigation of a high E.S.R.
对107例红细胞沉降率（E.S.R.）较高的患者在体外去纤维蛋白前后进行了红细胞沉降率测定。去纤维蛋白后红细胞沉降率的降低与纤维蛋白原水平相关，而去纤维蛋白后红细胞沉降率与球蛋白水平相关。去纤维蛋白后红细胞沉降率与去纤维蛋白前（即标准）红细胞沉降率的比值因疾病不同而有所变化；当球蛋白过多导致红细胞沉降率升高时该比值最高，而当纤维蛋白原过多时该比值最低。测定去纤维蛋白后的红细胞沉降率快速简便，可能有助于对红细胞沉降率升高进行初步检查。
