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The properties of the multicopy suppressor of the ogd1 mutation in yeast.

作者信息

Gbelská Y, Mockovciaková D, Timko J, Subík J

机构信息

Comenius University, Department of Microbiology and Virology, Bratislava, Slovakia.

出版信息

J Basic Microbiol. 1995;35(4):229-32. doi: 10.1002/jobm.3620350406.

DOI:10.1002/jobm.3620350406
PMID:7473064
Abstract

The 8.1 kb chromosomal fragment partially suppressing the ogd1 mutation in Saccharomyces cerevisiae has been cloned. The molecular analysis revealed that its suppressor gene codes for a natural glutamine tRNA(CAG) and maps on chromosome XIII in the upstream region of the URA10 gene. The multicopy plasmids containing this tRNA gene also suppressed the standard trp1-1 amber mutation and conferred the sensitivity of yeast cells to paromomycin and increased temperature.

摘要

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1
The properties of the multicopy suppressor of the ogd1 mutation in yeast.
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2
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