Armstrong D G, Liswood P J, Todd W F
Department of Orthopaedics/Podiatry, University of Texas Health Science Center, San Antonio, USA.
J Am Podiatr Med Assoc. 1995 Oct;85(10):533-7. doi: 10.7547/87507315-85-10-533.
This retrospective study reviewed the culture results of 112 admissions to a multidisciplinary diabetic foot care team with a primary diagnosis of infected diabetic pedal ulceration. An average of 1.5 +/- 0.9 species per patient (P < 0.0001) were isolated. Eighty-nine percent of wounds cultured grew two or fewer organisms. Anaerobic species were isolated in only 5% of all cultures. Of these isolates, the distinction between anaerobic colonization and true anaerobic infection is made. Results suggest that aggressive early hospitalization, coupled with aggressive intraoperative debridement, may yield less microbiologically complex infections that may be controlled with less expensive narrow spectrum antibiotic therapy. Diagnosis of the infected pedal ulceration of a patient with diabetes is a clinical one. If this diagnosis is combined with appropriate surgical intervention, microbiologic correlation, and antimicrobial therapy, the result may be a less complex hospital course and improved outcome.
这项回顾性研究分析了112例因原发性感染性糖尿病足溃疡而收治于多学科糖尿病足护理团队的患者的培养结果。每位患者平均分离出1.5±0.9种细菌（P<0.0001）。89%的伤口培养出两种或更少的微生物。仅5%的培养物分离出厌氧菌。在这些分离菌中，区分了厌氧定植和真正的厌氧感染。结果表明，积极的早期住院治疗，再加上积极的术中清创，可能会产生微生物学上不太复杂的感染，这些感染可用较便宜的窄谱抗生素治疗加以控制。糖尿病患者感染性足部溃疡的诊断是临床诊断。如果将这一诊断与适当的手术干预、微生物学关联和抗菌治疗相结合，结果可能是住院过程不太复杂且预后改善。
