Kao L W, Giles H R
Department of Obstetrics and Gynecology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, USA.
J Reprod Med. 1995 Aug;40(8):585-9.
To determine if laser-assisted anastomosis is superior to microsurgical anastomosis and laser welding for tubal reconstruction.
Sixty uterine tubes from 30 rabbits were transected and then anastomosed with a microsurgical technique, laser welding and laser-assisted anastomosis using a microscope. The rabbits were mated one month postoperatively and examined for implantation sites and adhesion formation three to seven days postpartum.
The amount of time required to perform laser-assisted anastomosis as well as laser welding was significantly shorter than for microsurgery. All the tubes withstood the distension pressure of pregnancy with the exception of 1 of the 20 laser-welded tubes, which had 30% of its circumference dehisced. There was no difference in the number of implantation sites per tube between the different groups. The anastomotic sites were well healed and were nonidentifiable except for holding stitches and microsurgical sutures.
Laser-assisted anastomosis and laser welding took less time to perform than microsurgery. Laser-assisted anastomosis resulted in excellent healing, as did microsurgery. With the protection of serum albumin, laser-assisted anastomosis did not cause any thermal damage, and the anastomotic sites could tolerate the distension pressure of pregnancy and parturition without problems. Laser welding without protection of serum albumin could cause thermal damage and dehiscence. The implantation and pregnancy rates were comparable The implantation and pregnancy rates were comparable with all three types of procedure.
确定激光辅助吻合术在输卵管重建方面是否优于显微外科吻合术和激光焊接术。
取自30只兔子的60条输卵管被切断,然后分别采用显微外科技术、激光焊接术以及在显微镜下进行激光辅助吻合术进行吻合。术后1个月让兔子交配,并在产后3至7天检查着床部位及粘连形成情况。
进行激光辅助吻合术和激光焊接术所需的时间明显短于显微外科手术。除了20条接受激光焊接的输卵管中有1条在其周长的30%处出现裂开外,所有输卵管均能承受妊娠时的扩张压力。不同组之间每条输卵管的着床部位数量没有差异。吻合部位愈合良好,除了定位缝线和显微外科缝线外无法区分。
激光辅助吻合术和激光焊接术的操作时间比显微外科手术短。激光辅助吻合术与显微外科手术一样,均实现了良好的愈合。在血清白蛋白的保护下,激光辅助吻合术未造成任何热损伤,吻合部位能够耐受妊娠和分娩时的扩张压力而无问题。未用血清白蛋白保护的激光焊接可能会造成热损伤和裂开。三种手术方式的着床率和妊娠率相当。