Swales J D
Department of Medicine, University of Leicester, Leicester Royal Infirmary, UK.
J Hum Hypertens. 1995 Jun;9(6):517-21.
Modern attempts to link intake of salt with population blood pressure (BP) show striking similarity to early 19th century attitudes which attributed human disease and premature death to inappropriate diet. Under these circumstances there is a danger that conviction of the truth of a hypothesis may lead to selection of evidence. A pooled meta-analysis of rigorously conducted studies of the effect of salt restriction on BP has been carried out. This indicates small but real effects in hypertensive patients although the degree of heterogeneity cannot be assessed. The effect in normotensive subjects is minimal and throws doubt on the value of general reduction in salt intake in lowering population BP.
现代将盐摄入量与人群血压（BP）联系起来的尝试，与19世纪早期认为人类疾病和过早死亡归因于不当饮食的观点有着惊人的相似之处。在这种情况下，存在一种风险，即对假设真实性的坚信可能导致对证据的选择性采纳。已对严格开展的盐限制对血压影响的研究进行了汇总荟萃分析。这表明盐限制对高血压患者有微小但真实的影响，尽管异质性程度无法评估。对血压正常者的影响微乎其微，这使人对普遍减少盐摄入量以降低人群血压的价值产生怀疑。
