Harris Y, Gorelick P B, Freels S, Billingsley M, Brown N, Robinson D
Department of Neurological Science, Rush Medical Center, Chicago, IL 60612, USA.
J Natl Med Assoc. 1995 Oct;87(10):741-5.
To better understand risk factors for Alzheimer's disease and vascular dementia, demographic, medical, and other epidemiological factors were compared for 83 African-American women with Alzheimer's disease and 46 with vascular dementia. Overall, the risk-factor profiles for Alzheimer's disease and vascular dementia were similar to those in other studies. However, Alzheimer's patients had a high frequency of hypertension and a relatively high frequency of diabetes mellitus. The presence of such risk factors raises the possibility that there is a vascular component to the dementia in these African-American women with Alzheimer's disease. Neuropathological studies are needed to help answer this question.
为了更好地了解阿尔茨海默病和血管性痴呆的风险因素,对83名患有阿尔茨海默病的非裔美国女性和46名患有血管性痴呆的女性的人口统计学、医学及其他流行病学因素进行了比较。总体而言,阿尔茨海默病和血管性痴呆的风险因素特征与其他研究相似。然而,阿尔茨海默病患者高血压的发生率较高,糖尿病的发生率也相对较高。这些风险因素的存在增加了一种可能性,即这些患有阿尔茨海默病的非裔美国女性的痴呆存在血管方面的因素。需要进行神经病理学研究来帮助回答这个问题。