Nakajima S, Wada Y, Kawai T, Kitaura K, Souma A, Enmoto T, Oka T
Department of Surgery II, Kyoto Prefectural University of Medicine, Japan.
Kyobu Geka. 1995 Sep;48(10):845-8.
Seven adult patients (> or = 40 years old) and six pediatric patients with incomplete endocardial cushion defect (ECD) underwent corrective surgery in our institution. Preoperative catheterization study showed that the left-to-right shunting rate and the pulmonary-to-systemic flow ratio were greater in adult patients than those in pediatric patients, but systolic pulmonary arterial pressure was not high and similar in the two groups. The degree of mitral regurgitation by left ventriculography was mild or moderate in both groups. However, in adult patients, a variety of arrhythmias were observed. Postoperatively, NYHA grades and arrhythmia improved markedly in the adult patients. Surgical correction for ECD is recommended even in adult patients before aggravation of cardiac failure and arrhythmia.
7例成年患者（≥40岁）和6例患有不完全性心内膜垫缺损（ECD）的儿科患者在我院接受了矫正手术。术前心导管检查显示，成年患者的左向右分流率和肺循环与体循环血流量之比高于儿科患者，但两组的收缩期肺动脉压均不高且相似。两组通过左心室造影显示的二尖瓣反流程度均为轻度或中度。然而，成年患者中观察到了多种心律失常。术后，成年患者的纽约心脏协会（NYHA）分级和心律失常明显改善。即使是成年患者，也建议在心力衰竭和心律失常加重之前进行ECD的手术矫正。
