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[一例原发性肺隐球菌病]

[A case of primary cryptococcosis of the lung].

作者信息

Yamamoto M, Hino M, Kayano K, Takeo M, Kouri Y, Mizuno Y, Meguro F

机构信息

Department of Surgery, Kobe West City Hospital, Japan.

出版信息

Kyobu Geka. 1995 Sep;48(10):883-6.

PMID:7474594
Abstract

A 37-year-old man was pointed out having an abnormal shadow in the right lung field at a medical checkup in July 1992. There was 5-year life history of rearing about 60 macaws since 10 years before. Upon operation a tumor 1.5 cm in diameter was palpated in the right S6. Intraoperative frozen section diagnosis revealed no malignancy. Partial excision was performed. The excised specimen showed a 1.5 x 1.4 x 1.0 cm, well-defined and yellowish white tumor. Histologically it was granuloma with a thin fibrous capsula, and most of the granuloma necrotized involving cryptococcus formans. Postoperative serum cryptococcus antigen and antibody titers were negative. There has been no sign of recurrence, as of 8 months after the operation. No adjuvant chemotherapy has been needed.

摘要

一名37岁男性在1992年7月的体检中被指出右肺野有异常阴影。自10年前起有饲养约60只金刚鹦鹉的5年经历。手术时在右S6可触及一个直径1.5厘米的肿瘤。术中冰冻切片诊断未发现恶性病变。进行了部分切除。切除标本显示为一个1.5×1.4×1.0厘米、边界清晰的黄白色肿瘤。组织学上为有薄纤维包膜的肉芽肿,大部分肉芽肿坏死,累及新型隐球菌。术后血清隐球菌抗原和抗体滴度均为阴性。截至手术8个月后,无复发迹象。无需辅助化疗。

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