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[良性前列腺增生病例中血清前列腺特异抗原值与前列腺内腺重量的关系]

[The relationship between serum PSA value and the weight of the inner gland of the prostate in the cases of benign prostatic hyperplasia].

作者信息

Wu B, Itoh Y, Saitoh M, Watanabe H

机构信息

Department of Urology, Kyoto Prefectural University of Medicine.

出版信息

Nihon Hinyokika Gakkai Zasshi. 1995 Oct;86(10):1525-9. doi: 10.5980/jpnjurol1989.86.1525.

DOI:10.5980/jpnjurol1989.86.1525
PMID:7474601
Abstract

BACKGROUND

To study reasons why serum PSA value (Markit-F) elevates in benign prostatic hyperplasia (BPH).

METHODS

The relationship between total prostatic weight and the outer gland weight in 48 cases of BPH undergoing subcapsular prostatectomy was studied by ultrasound measurement. PSA was compared with prostatic weight, inner gland weight, outer gland weight, growth speed of the inner gland and age in the 48 cases.

RESULTS

  1. The weight of the outer gland increased slightly in proportion to the development of BPH. However, the increase was not significant statistically. 2) PSA correlated with the inner gland weight and growing speed of the inner gland well. 3) PSA did not correlate with the outer gland weight and age.

CONCLUSIONS

It is well known that PSA elevates not only in the cases of prostatic cancer but also in the cases of BPH and that PSA correlates with the whole prostatic weight. This study revealed that the elevation of PSA in the cases of BPH was caused by enlargement of the inner gland.

摘要

背景

研究良性前列腺增生（BPH）患者血清前列腺特异抗原（PSA）值（化学发光法）升高的原因。

方法

对48例行前列腺包膜下切除术的BPH患者，通过超声测量研究前列腺总重量与外腺重量之间的关系。比较48例患者的PSA与前列腺重量、内腺重量、外腺重量、内腺生长速度及年龄。

结果

1）外腺重量随BPH进展略有增加，但差异无统计学意义。2）PSA与内腺重量及内腺生长速度密切相关。3）PSA与外腺重量及年龄无关。

结论

众所周知，PSA不仅在前列腺癌患者中升高，在BPH患者中也会升高，且PSA与前列腺总重量相关。本研究表明，BPH患者PSA升高是由内腺增大所致。

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