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步行对女性血清脂质和脂蛋白的急性影响。

Acute effects of walking on serum lipids and lipoproteins in women.

作者信息

Pronk N P, Crouse S F, O'Brien B C, Rohack J J

机构信息

University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA, USA.

出版信息

J Sports Med Phys Fitness. 1995 Mar;35(1):50-8.

PMID:7474993
Abstract

The purpose of this study was to characterize and evaluate the acute effects of walking performed of fairly light (50% VO2max) and moderate (70% VO2max) intensities on serum lipids and lipoproteins in a group of premenopausal (n = 11) and a group of postmenopausal (n = 10) women. Premenopausal women were (x +/- SEM) 34.5 +/- 1.1 years of age, had 22.8 +/- 1.7% body fat and a 2.47 +/- 0.08 l.min-1 VO2max. Postmenopausal women were 54.8 +/- 2.5 years of age, had 37.9 +/- 0.9% body fat and a 2.06 +/- 0.15 l.min-1 VO2max. All subjects walked on a motor-driven treadmill at each respective intensity of exercise for a total duration sufficient to expend 350 kcal of energy. Dependent variables included total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and its subfractions HDL2-C and HDL3-C, low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG). Blood samples were obtained at baseline (pre-exercise), immediately post-exercise (IPE), and at 24 hours and 48 hours post-exercise. A repeated measures design was employed controlling for diet, menstrual cycle periodicity, natural menopause, and plasma volume shifts. A 2 x 4 ANOVA was used to test for differences among means for each group separately. Significant (p < 0.05) time exercise intensity interactions were found for TC and LDL-C for the premenopausal women. This non-parallel change across exercise intensity condition created significant differences at IPE for both TC and LDL-C. Furthermore, an IPE increase in TG (p < 0.05) was observed.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本研究的目的是描述和评估在一组绝经前(n = 11)和一组绝经后(n = 10)女性中,进行相当轻度(50%最大摄氧量)和中度(70%最大摄氧量)强度步行对血清脂质和脂蛋白的急性影响。绝经前女性的年龄为(x±标准误)34.5±1.1岁,体脂率为22.8±1.7%,最大摄氧量为2.47±0.08升/分钟。绝经后女性的年龄为54.8±2.5岁,体脂率为37.9±0.9%,最大摄氧量为2.06±0.15升/分钟。所有受试者在电动跑步机上以各自的运动强度行走,总时长足以消耗350千卡能量。因变量包括总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)及其亚组分HDL2-C和HDL3-C、低密度脂蛋白胆固醇(LDL-C)以及甘油三酯(TG)。在基线(运动前)、运动后即刻(IPE)、运动后24小时和48小时采集血样。采用重复测量设计,控制饮食、月经周期、自然绝经和血浆容量变化。使用2×4方差分析分别检验每组均值之间的差异。在绝经前女性中,发现TC和LDL-C存在显著(p<0.05)的时间-运动强度交互作用。这种在不同运动强度条件下的非平行变化在IPE时导致TC和LDL-C均出现显著差异。此外,观察到IPE时TG升高(p<0.05)。(摘要截短至250字)

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