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[抗寄生虫制剂的制造技术。4. 生产细分散形式驱虫药溴克生的技术开发及其抗片形吸虫病活性评估]

[The technology for manufacturing antiparasitic preparations. 4. The development of a technology for producing the anthelmintic bromoksan in finely dispersed form and the evaluation of its antifascioliasis activity].

作者信息

Mikhaĭlitsyn F S, Petrov Iu F, Bol'shakova A Iu, Lebedeva M N, Lychko N D

出版信息

Med Parazitol (Mosk). 1995 Jul-Sep(3):41-2.

PMID:7476682
Abstract

A manufacturing procedure has been developed to prepare the anthelmintic bromoxane as a finely divided dosage form. The maximum toxic dose of the drug was 1 g per kg mice body weight. Its therapeutic dose in sheep fascioliasis was 20 mg/kg.

摘要

已经开发出一种制造工艺来制备驱虫药溴氧烷的细分剂型。该药物的最大毒性剂量为每千克小鼠体重1克。其在绵羊肝片吸虫病中的治疗剂量为20毫克/千克。

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