Iwamuro Y, Miyake H, Akiyama Y, Ito T, Kumai J, Matsumoto Y, Sugino T
Department of Neurosurgery, Hamamatsu Rosai Hospital.
No Shinkei Geka. 1995 Nov;23(11):1045-9.
The patient was a 10-year-old boy. He had a sudden onset of generalized tonic-clonic convulsion. On admission, he presented with mild disturbance of consciousness and right hemiparesis. The electroencephalogram showed diffuse spike and slow wave complex. Three days later, magnetic resonance imaging (MRI) showed high signal intensity areas in the left cerebellar hemisphere and pons. On cerebral angiograms, coiling of the bilateral carotid arteries, occlusion of the basilar artery at the distal site, and fenestration of the left vertebral artery at the atlanto-axis level were shown. According to these findings, the patient was diagnosed with brainstem and cerebellar infarction. On the follow-up angiograms, recanalization of the basilar artery on the right vertebral angiogram, occlusion of the left vertebral artery at the distal site of the posterior inferior cerebellar artery origin, and occlusion of one of the duplicated vertebral arteries were recognized. Fenestration of the vertebral artery is presented in about 1-2% at angiography and autopsy and the clinical significance is controversial. In this case, the fenestration may have played a role as an embolic source because there was no probable cause of the cerebral infarction, and the vascular occlusion and recanalization occurred near the distal site of the fenestration. These findings suggest the clinical significance of vertebral artery fenestration as an embolic source.
该患者为一名10岁男孩。他突然出现全身性强直阵挛性惊厥。入院时,他表现为轻度意识障碍和右侧偏瘫。脑电图显示弥漫性棘慢复合波。三天后,磁共振成像(MRI)显示左小脑半球和脑桥有高信号强度区域。脑血管造影显示双侧颈动脉盘绕、基底动脉远端闭塞以及寰枢椎水平左侧椎动脉开窗。根据这些发现,该患者被诊断为脑干和小脑梗死。在后续的血管造影中,右椎动脉造影显示基底动脉再通,左椎动脉在小脑后下动脉起源远端闭塞,且一条重复的椎动脉闭塞。椎动脉开窗在血管造影和尸检中的发生率约为1% - 2%,其临床意义存在争议。在本病例中,由于脑梗死没有可能的病因,且血管闭塞和再通发生在开窗远端附近,开窗可能起到了栓子来源的作用。这些发现提示椎动脉开窗作为栓子来源的临床意义。